Protein Purification
Selleck Chemical LLC Rapamycin (Sirolimus) 10mM/1mL 53123-88-9 AY 22989NSC-2260804
Rapamycin (Sirolimus, AY 22989, NSC-2260804) is a specific mTOR inhibitor with IC50 of ~0.1 nM HEK293 cells. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Cell Biolabs Inc ViraBind™ Adenovirus Miniprep Kit, 10 preps
Cell Biolabs' ViraBind™ Adenovirus Miniprep Kit provides fast purification of adenovirus supernatant with high yields. The kit uses a special spin column to purify supernatant from a single T75 flask or 10cm dish per prep in about 30 minutes. Total adenovirus recovery is >95%. The kit is suitable for 10 preps.
Reprocell Stemolecule Y27632, 10 mg, cell-permeable small molecule, reversible ATP-competitive ROCK inhibitor, white solid, inhibits ROCK1 (220 nM), ROCK2 (300 nM), >97% purity
Stemolecule Y27632 is a cell-permeable small molecule that serves as a highly potent and selective inhibitor of Rho-associated kinase (ROCK), specifically targeting ROCK1 and ROCK2. This compound is extensively utilized in stem cell research to enhance the survival and cloning efficiency of dissociated human embryonic stem (ES) cells without compromising their self-renewal properties and pluripotency. Additionally, it improves the survival of ES cell-derived neural precursors during transplantation and significantly enhances cell recovery after cryopreservation when combined with Pifithrin-u.
- Molecular target: Rho-associated kinase (ROCK)
- Mechanism of action: Reversible ATP-competitive inhibitor
- Inhibitory concentration (Ki): ROCK1 220 nM, ROCK2 300 nM
- Purity: >97% by HPLC
- Formulation: White solid
- Solubility: Reconstitute in DMSO
- Pack size: 10 mg
Selleck Chemical LLC EHop-016 10mg 1380432-32-5
EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 ?M for Rac1 in MDA-MB-435 and MDA-MB-231 cells, equally potent inhibition for Rac3. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Omega Biotek Inc E.Z.N.A. Viral RNA Kit
The E.Z.N.A. Viral RNA Kit is designed for the isolation of viral DNA and viral RNA from cell-free fluids such as plasma, serum, urine and cell culture supernatant. The procedure completely removes contaminants and enzyme inhibitors making viral RNA isolation fast, convenient and reliable. The kit is also suitable for the isolation of total RNA from cultured cells, tissues and bacteria. RNA purified using the E.Z.N.A. Viral RNA method is ready for all downstream applications such as RT-PCR.
Echelon Biosciences Research Labs PKC Isoenzyme Inhibitor PKC Y translocation peptide - 1 mg,
PKC Isoenzyme Inhibitor PKC Y translocation peptide - 1mg , Glu-Ala-Val-Ser-Leu-Lys-Pro-Thr-OH Category/Application: Inhibitor This item is non returnable
Worthington Biochemical Corporation RECMB SERRATIA MARC-NUCLE 25KU
Recombinant Serratia marcescens nuclease produced in Komagataella phaffi. Chromatographically purified. Free of animal derived components and proteases. A liquid preparation in 20mM Tris-HCl, 2mM MgCl2, 20mM NaCl, pH 8.0 and 50% glycerol. Store at -20°C. 25 KU
Abcam (-)-Nutlin-3, p53-MDM2 binding inhibitor, 25MG
MW 581.5 Da, Purity >98%. Potent p53-MDM2 binding inhibitor (IC50 = 90 nM). Enantiomer of (+)-Nutlin-3 (ab144426). Shows antiproliferative effects (IC50 values are 2.2 and 1.3 µM for human skin and murine fibroblasts respectively). Shows antitumor effects *in vivo.* Orally active.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical FOXM1 InhIbItr III 25mg
An inhibitor of FOXM1 DNA-binding activity (IC50 = 22.5 µM); binds to FOXM1 and is selective for inhibiting FOXM1 transcriptional activity over FOXA1, FOXA2, FOXP2, and GATA-1 transcriptional activity; inhibits the growth of MCF-7, MDA-MB-231, and PEO1 cancer cells (GI50s = 18, 21.8, and 18.1 µM, respectively)
Abcam RKRARKE, PKG Inhibitor, 5MG
MW 943.12 g/mol, Purity >99%. Competitive protein kinase G (PKG) inhibitor. Ki = 86 µM for PKG; Ki = 550 µM for PKA. Potential inhibitory activity in neuronal systems.
The product is subject to the following: Abcam Restricted Use Statement
Ubpbio Empty 12ml capacity column for gravity purification, 5 columns per pack
This column serves as a tool for gravity purification using small quantities of resin. The package contains 5 columns with their top and end caps. The PLASTIC 1ML COLUMNs are polypropylene with a total volume of 12 ml and contain a polyethylene frit with a nominal pore size of 20 µm. They are specially designed for working with bed volumes of 0.5-2.0 ml.
Abcam Serine Protease Assay Kit (SR101-Leu-CMK), 25 Tests
These Serine Protease Assay Kits enable researchers to detect intracellular chymotrypsin-like serine protease activity in vitro without lysing the cell.
The product is subject to the following: Abcam Restricted Use Statement
Echelon Biosciences Research Labs D-Erythro-Sphingosine 10 mg
Sphingosine is formed through ceramidase catalyzed hydrolysis of ceramide. It is a potent inhibitor of protein kinase C (IC50 = 1-3 M). Sphingosine is phosphorylated by sphingosine kinase to the bioactive lipid sphingosine 1-phosphate This item is non returnable